Total Dietary Flavonoid Intake & Cardiometabolic Disease Risk
Several epidemiological studies have suggested that flavonoid intake is associated with a decreased risk of cardiometabolic disease. A recently published meta-analysis involving 47 articles and including 1346676 participants was conducted to evaluate the associations between flavonoid intake and cardiometabolic disease and to explore their dose-response relationships . The meta-analysis finding from the quantitative data suggested that a higher level of flavonoid intake is beneficial for the prevention of cardiometabolic diseases, with a linearity dose-response association between total flavonoid intake and cardiovascular disease .
My research on polyphenols has established that the doses of polyphenols from dietary sources are insufficient to exert the desired physiochemical effects of these polyphenols. Scientific evidence has been gathering to support the nutraceutical properties of polyphenols at doses beyond those achieveable from dietary sources.
1. Li, Tianze, Zhao, Yang, Yuan, Lijun, Zhang, Dongdong, Feng, Yifei, Hu, Huifang, Hu, Dongsheng & Liu, Jiaye. 2022. Total dietary flavonoid intake and risk of cardiometabolic diseases: A dose-response meta-analysis of prospective cohort studies. Critical Reviews in Food Science and Nutrition 1-13.