Omega-3 and Omega-6 Intakes on Leukocyte Telomere Length
A telomere is a region of repetitive nucleotide sequences associated with specialized proteins at the ends of linear chromosomes. Telomere length declines with age in most human tissues, and a shorter telomere length is thought to accelerate senescence. Telomere length is an indicator of human biological age.
Oxidative stress and inflammation have been associated with telomere shortening. Limited evidence is available to relate the intakes of omega-3 and omega-6 fatty acids to telomere shortening. A recently published cross-sectional study examined the associations of total or individual omega-3 or total omega-6 fatty acid intake with leukocyte telomere length in 2,494 US males . The study finding suggests that higher intakes of docosahexaenoic acid (an omega-3 fatty acid) and canned tuna consumption are associated with longer leukocyte telomere length .
1. Seo, Bojung, Yang, Keming, Kahe, Ka, Qureshi, Abrar A, Chan, Andrew T, De Vivo, Immaculata, Cho, Eunyoung, Giovannucci, Edward L & Nan, Hongmei. 2022. Association of omega-3 and omega-6 fatty acid intake with leukocyte telomere length in US males. The American Journal of Clinical Nutrition