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How can functional food improve heart related issues?
Functional Food

How can functional food improve heart related issues?

In addition to adopting good dietary habits, we can protect ourselves from cardiovascular disease (CVD) by consuming food with scientifically validated functional or nutraceutical ingredients. 

 

How do we know if the food contains “cardioprotective” functional or nutraceutical ingredients? 

 

First, we need to understand how CVD arises. 

 

Atherosclerosis, the obstruction of normal blood flow due to the buildup of fat tissue in the blood vessel wall, is the most common cause of CVD1

 

Scientists and clinicians have studied atherosclerosis for decades and identified its pathogenesis mechanisms. 

 

The most established mechanism is the oxidative modification of low-density lipoprotein (LDL)1

 

Atherosclerosis may be prevented or delayed if the LDL oxidative modification process is retarded or attenuated. 

 

Antioxidants may work to slow down the oxidative modification process of LDL2

 

So is the intake of antioxidants sufficient to delay or stop atherosclerosis? 


 

1. Stocker, Roland & Keaney, John F., Jr.. 2004. Role of oxidative modifications in atherosclerosis. Physiol Rev 84: 1381-1478.

 

2. Niki, Etsuo. 2018. Oxidant-specific biomarkers of oxidative stress. Association with atherosclerosis and implication for antioxidant effects. Free Radical Biology and Medicine 120: 425-440. 

posted on 14 May 2021
Posted by Dr. Loke Wai Mun

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