ENJOY FREE DELIVERY IN SINGAPORE WITH A MINIMUM ORDER OF $27
0

Diet & Circulating Short-Chain Fatty Acids
Functional Food

Diet & Circulating Short-Chain Fatty Acids

Continuing from my last post on healthy gut microbiota, you may start wondering how the gut microbiota can affect our health. One proposed mechanism is via the production of short-chain fatty acids from food, which is a complex and dynamic saccharolytic fermentation process mediated by both human and gut microbial factors. 

 

 

A randomized, controlled, crossover trial reported the temporal changes in short-chain fatty acid concentrations in response to 2 contrasting diets, a diet with high adherence to WHO healthy eating recommendations and a typical Western diet.[1] The unhealthy western diet was found to associate with a lower concentration of circulating short-chain fatty acids.[1] The results provide evidence supporting the roles of short-chain fatty acids mediating the effects of gut-brain axis.

 

 

Brignardello, Jerusa, Fountana, Sofia, Posma, Joram Matthias, Chambers, Edward S, Nicholson, Jeremy K, Wist, Julien, Frost, Gary, Garcia-Perez, Isabel & Holmes, Elaine. 2022. Characterization of diet-dependent temporal changes in circulating short-chain fatty acid concentrations: A randomized crossover dietary trial. The American Journal of Clinical Nutrition doi: 10.1093/ajcn/nqab211. 12/13/2022

 

Posted by Dr. Loke Wai Mun