What is so special about avocado? Avocado is comparatively rich in unsaturated fat and fiber among the fruits and vegetables. Diets emphasizing unsaturated fat are associated with reducing cardio-metabolic risk factors. Questions arise about the benefits of consuming more avocados.
A recent published study assessed the replacement of carbohydrate energy with avocado energy for 12 weeks on glucose homeostasis and cardio-metabolic risk factors in free-living adults diagnosed with metabolic syndrome. Dietary total, mono- and poly-unsaturated fat, fiber, and vegetable intake were expectedly higher in the avocado group compared to non-avocado group. Body weight or composition did not differ between the two groups. Avocado intervention tends to improve glucose homeostasis in these metabolic-compromised adults, but results lacked significance. Nevertheless with insignificant results, the authors suggested favorable health trends and encouraged the caloric replacement of carbohydrate with avocado.
In my opinion, though avocado may be a good source of plant-based unsaturated fat, carbohydrate replacement with avocado may not be wise considering the limited supporting evidence. The keyword is still moderation!
 Zhang, Xuhuiqun, Xiao, Di, Guzman, Gabriela, Edirisinghe, Indika & Burton-Freeman, Britt. 2022. Avocado consumption for 12 weeks and cardio-metabolic risk factors: a randomized controlled trial in adults with overweight or obesity and insulin resistance. The Journal of Nutrition doi: 10.1093/jn/nxac126.